The Pope, who had strong views concerning the project's design, selected Bernardo Rossellino as the architect for this project.
The Palazzo Piccolomini is important in the history of palace design for its early use of pilasters. These classical features were first seen in domestic architecture on the façade of the Palazzo Rucellai in Florence. By the end of the fifteenth century, pilasters were also utilized on palace façades in Rome.
Bernardo was familiar with the façade of the Palazzo Rucellai because he supervised its construction. Although Alberti is traditionally credited with the design, some architectural historians consider Bernardo to have been its architect.
|=||Pilasters carrying entablatures. The façades of both palaces are articulated on all three stories by pilasters carrying string courses detailed as entablatures.|
|=||Smooth rustication. The masonry on all three stories of both palaces utilizes smooth rustication in which dressed stone is laid with prominent joints.|
|=||Base detailed as pedestals of pilasters. The bases of both palaces include the detailing of pedestals under the pilasters, but the detailing of the Palazzo Piccolomini is less distinct. (Alberti used bases to adjust column heights so that columns could be proportioned in accordance with their individual orders regardless of the heights of the individual stories.) The benches and hitching rings are features that were common to other palaces as well.|
|=||Vertically aligned windows. The windows of both palaces are aligned vertically, unlike many other palaces at mid-century. The windows of both, like most fifteenth-century Florentine palaces, were rectangular on the ground story and biforate on the upper stories.|
Several features distinguish the Palazzo Piccolomini from the Palazzo Rucellai.
|●||Wider window spacing and less enframement. The windows are further apart on the Palazzo Piccolomini than on the Palazzo Rucellai, and the masonry around them is treated differently. On the Palazzo Rucellai the windows appear to have frames because the stones along their sides are uniform in width, forming a columnar grouping, but on the Palazzo Piccolomini, the blocks framing the windows vary in width because they are part of the bond.|
|●||Rustication of ground-story pilasters. The pilasters on the ground story of the Palazzo Piccolomini are rusticated, which makes them blend in with the wall rather than stand out like the smooth ashlar pilasters on its upper stories and on all three stories of the Palazzo Rucellai. This gives the lower story a coarser texture than the stories above, which was quite common on Renaissance palaces.|
The courtyard loggias vary in depth on the different facings. The entrance wing facing is slightly deeper than the side facings, and the loggia on the rear is around twice as deep as those on the sides.
The courtyard loggias are enclosed on three sides by wings containing rooms and on the fourth side by an outward-facing loggia.
The Palazzo Piccolomini has loggias on all three floors of the garden facing. These loggias, especially the highest one, provide a view of not only the garden but also the distant countryside. The pope was fond of this view and specified the palace's placement and use of loggias with it in mind.
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